Table 1.
Baseline Characteristics | n | Heart Failure Patients | n | Donors |
---|---|---|---|---|
Age, ya | 110 | 55.3 ± 12.2 | 107 | 48.0 ± 12.5 |
Gender (male/female) | 110 | 89/21 (81% male) | 107 | 55/52 (51% male) |
Ethnicity | 110 | 82% European | 106 | 96% European |
15% African American | ||||
3% Hispanic | 4% African American | |||
38/2 (81%/4%) | ||||
Cigarette smoking (past/present) | 47 | 27.0 ± 5.1 | ||
Body mass index, kg/m2a | 64 | 63.9 ± 8.7 | ||
Diastolic blood pressure, mm Hga | 78 | 97.2 ± 12.4 | ||
Systolic blood pressure, mm Hga | 78 | 3.7 (3.0–4.5) | ||
Total cholesterol, mmol/Lb | 87 | 1.9 (1.5–2.5) | ||
LDL, mmol/Lb | 87 | 1.1 ± 0.4 | ||
HDL, mmol/La | 87 | 1.2 (0.9–1.6) | ||
Triglycerides, mmol/Lb | 87 | 5.7 (4.9–6.8) | ||
Glucose, mmol/Lb | 94 | 174 (95–351) | ||
Brain natriuretic peptide, pmol/Lb | 82 | 15.7 ± 5.5 | ||
LVEF, %a | 94 | 106 (88–132) | 61 | 52% ± 15.3% |
Creatinine, μmol/Lb | 91 | 6.1 (2.6–10.1) | ||
Duration of heart failure, yb | 70 | 16 (17.4%) | ||
Family history of heart disease | 92 | 47 (47.0%) | ||
Previously diagnosed hypertension | 100 | 24 (24.0%) | ||
Type 2 diabetes | 100 | 48 (48.0%) | ||
Myocardial infarction | 100 | 58 (52.7%) | ||
ACE inhibitor treatment | 110 | 61 (55.5%) | ||
β-Blocker treatment | 110 | 69 (69.0%) | ||
Loop diuretic treatment | 100 | 52 (52.0%) | ||
Spironolactone treatment | 100 |
Abbreviations: ACE, angiotensin-converting enzyme; HDL, high-density lipoprotein; ; LDL, low-density lipoprotein; LVEF, LV ejection fraction.
Mean and SD.
Median and interquartile range.