Table 4.
In vitro development of mouse GV oocytes after PN embryos were microinjected with mimics of each miR-125 family member.
| number of embryos (%) |
||||||
|---|---|---|---|---|---|---|
| total | 2 cell | 3 cell | 4/8 cell | MO | BL | |
| negative control mimic | 57 | 0 (0.0) | 0 (0.0) | 10 (16.6) | 9 (17.0) | 38 (66.4) |
| miR-125a-5p mimic | 40 | 34 (84.2)a | 3 (7.9) | 3 (7.9) | 0 (0.0) | 0 (0.0)a |
| miR-125b-5p mimic | 31 | 17 (65.5)a | 12 (29.7) | 1 (2.2) | 1 (2.6) | 0 (0.0)a |
| miR-351-5p mimic | 42 | 29 (71.2)a | 9 (21.2) | 4 (7.6) | 0 (0.0) | 0 (0.0)a |
aValues are statistically significant at p<0.001 compared with the negative control mimic-injected group at the same stage.