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. 2016 Oct 18;10(Suppl 7):385–388. doi: 10.1186/s12919-016-0060-7

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Distribution of type I error rate by MAF. Type I error rate versus MAF. Different color/symbols indicate different null traits. Each point indicates average type I error rate at the critical level of 10^-5 of SNVs grouped by MAF; extremely rare variants (MAF < 0.0025) are classified by number of occurrences of the rare allele, while rare (0.0025 ≤ MAF < 0.05) and common (MAF ≥ 0.05) ones are classified by MAF range