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. 2016 Oct 18;10(Suppl 7):289–294. doi: 10.1186/s12919-016-0045-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Uniform Q-Q plots of the p values (on a − log₁₀ scale) for testing H ₀ : α ₁ = 0 under the copula model (left panel), univariate model (middle panel), and SKAT/SKAT-O (right panel). SNVs/genes which are significant after correcting for multiple testing are highlighted in blue color