Table 1.

Results of the SNVs significantly associated with SBP under the copula model and results under the univariate model

SNV	MAF	Location	Copula			Univariate
			$\widehat{{\mathit{\alpha }}_1}$ (SE)	p value	Adj. p value	$\widehat{{\mathit{\alpha }}_1}$ (SE)	p value	Adj. p value
rs10402825	0.04	CEACAM5 (protein coding)	30.77 (6.52)	2.40 × 10− 6	4.42 × 10− 2	32.21 (6.63)	6.18 × 10− 6	1.12 × 10− 1
rs7258524	0.04	CEACAM5 (upstream)	30.75 (6.56)	2.77 × 10− 6	4.42 × 10− 2	32.28 (6.67)	6.86 × 10− 6	1.71 × 10− 1

Adj. p value is the adjusted p value with BH-correction; MAF denotes the minor allele frequency in this sample. The estimated Kendall’s τ between SBP _adj and GE _CEACAM5,adj is − 0.13. Note: The markers are in very high linkage disequilibrium (LD) (r = 0.99). SNVs rs34155934, rs35091611, and rs10415940 in the same gene are in perfect LD with rs7258524 and have identical association