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. 2016 Oct 18;10(Suppl 7):309–313. doi: 10.1186/s12919-016-0048-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Comparison of p values testing for association between the gene-based MURAT test, and single-phenotype tests with either gene-based or single-SNP–based analyses, for 15 known hypertension-associated genes selected from the NIH-GWAS catalog, and occurring on odd-numbered chromosomes. For the single phenotype tests, Bonferroni corrections were applied to adjust the p values for testing 2 traits and, for single-variant test results, also for testing all SNPs in a gene