Table 1.
Summary of top 5 genes associated with SBP, DBP, and HTN
| Chr | BP1 | BP2 | Gene | PG+T | PG | PT | #SNV | |
|---|---|---|---|---|---|---|---|---|
| SBP | 1 | 27763371 | 27777626 | TMEM222 | 1.94E-003 | 1.61E-004 | 5.87E-001 | 100 |
| SBP | 17 | 5486374 | 5490814 | MIS12 | 1.63E-004 | 2.26E-003 | 4.46E-003 | 134 |
| SBP | 19 | 10528205 | 10581112 | PDE4A | 3.99E-004 | 1.30E-001 | 2.39E-004 | 311 |
| SBP | 3 | 57376936 | 57627630 | DNAH12 | 7.87E-003 | 2.65E-004 | 9.92E-001 | 1691 |
| SBP | 19 | 32291486 | 32313186 | MAG | 1.74E-003 | 7.61E-001 | 3.22E-004 | 216 |
| DBP | 11 | 72239077 | 72244176 | PHOX2A | 1.45E-005 | 4.17E-001 | 5.22E-006 | 112 |
| DBP | 19 | 58182989 | 58213562 | ZNF274 | 3.68E-004 | 4.03E-001 | 1.27E-004 | 234 |
| DBP | 3 | 10277571 | 10284767 | GHRL | 1.52E-004 | 4.94E-002 | 1.46E-004 | 118 |
| DBP | 11 | 43991253 | 44040694 | ALX4 | 4.16E-004 | 1.16E-003 | 2.20E-002 | 458 |
| DBP | 1 | 61681046 | 61725423 | TM2D1 | 5.52E-003 | 5.43E-004 | 7.86E-001 | 307 |
| HTN | 3 | 183042973 | 183066541 | TRA2B | 1.06E-005 | 4.91E-003 | 3.11E-005 | 496 |
| HTN | 7 | 27445802 | 27583281 | HIBADH | 4.05E-004 | 3.31E-005 | 7.38E-001 | 204 |
| HTN | 17 | 4004445 | 4143020 | ZZEF1 | 3.86E-005 | 2.24E-002 | 1.27E-004 | 871 |
| HTN | 3 | 57277865 | 57480169 | DNAH12 | 5.23E-003 | 1.13E-004 | 9.99E-001 | 327 |
| HTN | 5 | 131138142 | 131164051 | SLC22A5 | 2.58E-003 | 1.34E-004 | 9.12E-001 | 151 |
BP1 first base pair of the gene, BP2 last base pair of the gene, Chr chromosome, P G , P G+T , P T p values from 3 types of tests, and the bolded p value is the smallest of the 3 p values, #SNV number of single nucleotide variants in the gene region