Table 2. List of assigned statistically significant metabolites after comparison of PCV group with the control group.
| LipidIon | Ret Time (min) | Calc m/z | VIP | p-Value | Fold Change |
|---|---|---|---|---|---|
| UPLC-MS Positive Mode | |||||
| Higher in PCV | |||||
| LPC(20:4)+H* | 1.51 | 544.3397685 | 2.464 | 0.006 | 0.514 |
| PC(18:0/20:4)+H | 26.72 | 810.6007335 | 2.447 | 0.006 | 0.749 |
| SM(d16:0/22:2)+H* | 11.92 | 757.6218025 | 2.373 | 0.008 | 0.277 |
| PC(16:1p/20:4)+H | 9.72 | 764.5588685 | 2.185 | 0.016 | 3.503 |
| SM(d16:0/26:3)+Na* | 12.78 | 833.6506975 | 2.140 | 0.018 | 0.315 |
| PC(19:0/20:4)+H | 12.41 | 824.6163835 | 2.113 | 0.020 | 0.641 |
| PC(20:3/22:6)+H | 10.13 | 856.5850835 | 2.091 | 0.021 | 0.791 |
| PC(18:1/20:4)+H | 10.99 | 808.5850835 | 2.066 | 0.023 | 0.265 |
| PC(20:1p/19:1)+H | 13.03 | 812.6527685 | 2.040 | 0.025 | 0.521 |
| PC(16:0/22:5)+H | 11.48 | 808.5850835 | 2.038 | 0.025 | 0.765 |
| PC(17:1/20:4)+H | 10.41 | 794.5694335 | 2.033 | 0.026 | 0.811 |
| PC(18:1/24:7)+H | 10.60 | 858.6007335 | 1.986 | 0.029 | 0.689 |
| PC(17:0/20:4)+H | 11.32 | 796.5850835 | 1.936 | 0.034 | 0.532 |
| PC(16:0e/19:1)+H | 12.88 | 760.6214685 | 1.932 | 0.034 | 0.390 |
| LPC(20:1p)+H | 3.05 | 534.3918035 | 1.921 | 0.036 | 0.369 |
| SM(d16:0/20:1)+H* | 11.78 | 731.6061525 | 1.905 | 0.037 | 0.295 |
| SM(d22:1/19:1)+Na* | 13.26 | 821.6506975 | 1.896 | 0.038 | 0.411 |
| SM(d16:0/26:2)+Na | 13.73 | 835.6663475 | 1.893 | 0.039 | 0.312 |
| SM(d16:0/20:2)+H* | 10.79 | 729.5905025 | 1.821 | 0.047 | 0.240 |
| Lower in PCV | |||||
| PC(16:0e/22:6)+H | 11.71 | 792.5901685 | 2.184 | 0.016 | −2.139 |
| So(d16:0)+H | 27.82 | 274.2740555 | 2.164 | 0.017 | −0.933 |
| So(d22:1)+H | 1.89 | 356.3523055 | 2.138 | 0.018 | −0.620 |
| PE(18:2/18:2)+H | 10.27 | 740.5224835 | 2.087 | 0.022 | −0.693 |
| UPLC-MS Negative Mode | |||||
| Higher in PCV | |||||
| PAF(35:4)+HCOO | 11.43 | 840.5760105 | 2.169 | 0.008 | 0.441 |
| SM(d16:0/22:2)+HCOO* | 11.87 | 801.6127295 | 2.155 | 0.009 | 0.209 |
| LPA(20:4)-H | 1.66 | 457.2360665 | 2.036 | 0.014 | 0.741 |
| SM(d18:1/17:1)+HCOO | 10.26 | 759.5657795 | 2.004 | 0.015 | 0.281 |
| PAF(34:3)+HCOO | 11.56 | 828.5760105 | 1.933 | 0.020 | 0.372 |
| PC(17:0/22:6)+HCOO | 11.00 | 864.5760105 | 1.891 | 0.023 | 0.601 |
| LPC(20:4)+HCOO* | 1.56 | 588.3306955 | 1.872 | 0.024 | 0.326 |
| SM(d16:0/20:1)+HCOO* | 11.78 | 775.5970795 | 1.823 | 0.029 | 0.240 |
| PC(18:2/18:2)+HCOO | 10.65 | 826.5603605 | 1.801 | 0.031 | 0.205 |
| PAF(34:4)+HCOO | 10.83 | 826.5603605 | 1.794 | 0.032 | 0.204 |
| SM(d22:1/19:1)+HCOO* | 13.29 | 843.6596795 | 1.753 | 0.036 | 0.259 |
| phSM(d16:0/26:1)+HCO | 13.20 | 875.6858945 | 1.750 | 0.036 | 0.277 |
| LPC(22:5)+HCOO | 1.73 | 614.3463455 | 1.727 | 0.039 | 0.382 |
| PC(20:4/22:6)+HCOO | 9.38 | 898.5603605 | 1.703 | 0.042 | 0.497 |
| SM(d16:0/20:2)+HCOO* | 10.82 | 773.5814295 | 1.703 | 0.042 | 0.175 |
| SM(d18:1/19:0)+HCOO | 12.37 | 789.6127295 | 1.699 | 0.042 | 0.363 |
| PC(16:0e/22:4)+HCOO | 12.34 | 840.6123955 | 1.670 | 0.046 | 0.307 |
| PC(18:1/20:5)+HCOO | 10.19 | 850.5603605 | 1.659 | 0.048 | 0.367 |
| PC(18:0/20:3)+HCOO | 12.46 | 856.6073105 | 1.657 | 0.048 | 0.723 |
| PC(20:0p/20:4)+HCOO | 12.60 | 866.6280455 | 1.648 | 0.049 | 0.254 |
| SM(d16:0/26:3)+HCOO* | 12.91 | 855.6596795 | 1.644 | 0.050 | 0.232 |
| Lower in PCV | |||||
| LPA(18:2)-H | 1.82 | 433.2360665 | 2.756 | 0.001 | −1.153 |
| LPA(16:0)-H | 2.24 | 409.2360665 | 2.094 | 0.011 | −0.901 |
| LPA(18:1)-H | 2.39 | 435.2517165 | 1.823 | 0.029 | −0.905 |
(*) Detected with statistical significance in both polarities.
TGs, DGs were excluded.