Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 25;7:13177. doi: 10.1038/ncomms13177

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) 5hmC-5mC scatterplot for the highest 5hmC CpGs (n=3,876) with smooth curve fitted by loess across thirty glioblastomas. Each point represents a single CpG per tumour with the highest intensity values represented in red and lower intensity (that is, fewer signals) represented in blue. (b) The distribution of high 5hmC CpGs relative to the nearest canonical transcriptional start site (TSS) in kilo base pairs with category bins for genomic distance shown for both upstream and downstream of the TSS. Percentage of high 5hmC CpGs (n=3,876) are shown above each proportion. (c) Forest plot of odds ratios and 95% confidence intervals (Cochran-Mantel-Haenszel or Fisher's exact test) for enrichment of high 5hmC genomic regions against 450K background set. Numerical representation of the odds ratio and associated P-value for each genomic feature are also presented.