Table 2.
Statistically significant undirected edges of the functional networks – kainate-treated group > controls, under 1.5% isoflurane, as shown in Fig. 3A. Source and target nodes do not imply directional connectivity, and edge is non-directional, LH = left hemisphere; RH = right hemisphere.
| Source node | Target node | t-stat, P < 0.002 |
|---|---|---|
| Prelimbic cortex - LH | Orbitofrontal cortex - LH | 4.26 |
| Anterior cingulate cortex - LH | Nucleus accumbens core - LH | 4.53 |
| Anterior cingulate cortex - LH | Caudate putamen - LH | 3.87 |
| Primary somatosensory cortex - LH | Anterior cingulate cortex - LH | 3.63 |
| Piriform cortex - LH | Orbitofrontal cortex - LH | 4.39 |
| Piriform cortex - LH | Nucleus accumbens core - LH | 4.82 |
| Piriform cortex - LH | Caudate putamen - LH | 4.35 |
| Piriform cortex - LH | Anterior cingulate cortex - LH | 5.61 |
| Mediodorsal thalamic nuclei - LH | Nucleus accumbens core - LH | 3.78 |
| Mediodorsal thalamic nuclei - LH | Anterior cingulate cortex - LH | 4.49 |
| Mediodorsal thalamic nuclei - LH | Piriform cortex - LH | 4.53 |
| Amygdala - LH | Piriform cortex - LH | 3.87 |
| Hippocampus - LH | Anterior cingulate cortex - LH | 4.40 |
| Hippocampus - LH | Piriform cortex - LH | 3.86 |
| Auditory/temporal association cortex - LH | Anterior cingulate cortex - LH | 3.95 |
| Auditory/temporal association cortex - LH | Primary somatosensory cortex - LH | 3.78 |
| Posterior parietal cortex - LH | Nucleus accumbens core - LH | 4.34 |
| Posterior parietal cortex - LH | Anterior cingulate cortex - LH | 4.87 |
| Posterior parietal cortex - LH | Piriform cortex - LH | 4.63 |
| Posterior parietal cortex - LH | Hippocampus - LH | 3.83 |
| Orbitofrontal cortex - RH | Mediodorsal thalamic nuclei - LH | 5.24 |
| Orbitofrontal cortex - RH | Auditory/temporal association cortex - LH | 4.07 |
| Nucleus accumbens core - RH | Prelimbic cortex - LH | 3.51 |
| Nucleus accumbens core - RH | Nucleus accumbens core - LH | 4.21 |
| Nucleus accumbens core - RH | Anterior cingulate cortex - LH | 5.03 |
| Nucleus accumbens core - RH | Piriform cortex - LH | 4.97 |
| Nucleus accumbens core - RH | Mediodorsal thalamic nuclei - LH | 3.71 |
| Nucleus accumbens core - RH | Hippocampus – LH | 3.69 |
| Nucleus accumbens core - RH | Posterior parietal cortex - LH | 4.07 |
| Caudate putamen - RH | Anterior cingulate cortex - LH | 4.62 |
| Caudate putamen - RH | Orbitofrontal cortex - RH | 3.99 |
| Anterior cingulate cortex - RH | Prelimbic cortex - LH | 4.78 |
| Anterior cingulate cortex - RH | Nucleus accumbens core - LH | 4.53 |
| Anterior cingulate cortex - RH | Caudate putamen - LH | 3.87 |
| Anterior cingulate cortex - RH | Anterior cingulate cortex - LH | 4.76 |
| Anterior cingulate cortex - RH | Piriform cortex - LH | 4.50 |
| Anterior cingulate cortex - RH | Hippocampus - LH | 3.77 |
| Anterior cingulate cortex - RH | Auditory/temporal association cortex - LH | 3.99 |
| Anterior cingulate cortex - RH | Posterior parietal cortex - LH | 4.80 |
| Anterior cingulate cortex - RH | Nucleus accumbens core - RH | 4.58 |
| Anterior cingulate cortex - RH | Caudate putamen - RH | 4.03 |
| Piriform cortex - RH | Orbitofrontal cortex - LH | 3.87 |
| Piriform cortex - RH | Nucleus accumbens core - LH | 4.39 |
| Piriform cortex - RH | Posterior parietal cortex - LH | 3.52 |
| Piriform cortex - RH | Nucleus accumbens core - RH | 3.97 |
| Mediodorsal thalamic nuclei - RH | Prelimbic cortex - LH | 3.68 |
| Mediodorsal thalamic nuclei - RH | Anterior cingulate cortex - LH | 4.09 |
| Mediodorsal thalamic nuclei - RH | Piriform cortex - LH | 3.69 |
| Mediodorsal thalamic nuclei - RH | Piriform cortex - RH | 3.60 |
| Amygdala - RH | Nucleus accumbens core - LH | 3.72 |
| Amygdala - RH | Piriform cortex - LH | 3.66 |
| Amygdala - RH | Mediodorsal thalamic nuclei - LH | 3.77 |
| Amygdala - RH | Hippocampus - LH | 3.65 |
| Amygdala - RH | Posterior parietal cortex - LH | 3.69 |
| Amygdala - RH | Anterior cingulate cortex - RH | 3.62 |
| Amygdala - RH | Piriform cortex - RH | 4.07 |
| Hippocampus - RH | Anterior cingulate cortex - LH | 5.60 |
| Hippocampus - RH | Primary somatosensory cortex - LH | 3.90 |
| Hippocampus - RH | Piriform cortex - LH | 3.97 |
| Hippocampus - RH | Posterior parietal cortex - LH | 3.81 |
| Hippocampus - RH | Nucleus accumbens core - RH | 4.21 |
| Hippocampus - RH | Anterior cingulate cortex - RH | 4.17 |
| Auditory/temporal association cortex - RH | Anterior cingulate cortex - LH | 4.69 |
| Auditory/temporal association cortex - RH | Primary somatosensory cortex - LH | 3.98 |
| Auditory/temporal association cortex - RH | Auditory/temporal association cortex - LH | 3.57 |
| Auditory/temporal association cortex - RH | Nucleus accumbens core - RH | 4.69 |
| Auditory/temporal association cortex - RH | Anterior cingulate cortex - RH | 5.37 |
| Posterior parietal cortex - RH | Nucleus accumbens core - LH | 3.89 |
| Posterior parietal cortex - RH | Caudate putamen - LH | 3.62 |
| Posterior parietal cortex - RH | Anterior cingulate cortex - LH | 4.40 |
| Posterior parietal cortex - RH | Primary somatosensory cortex - LH | 3.51 |
| Posterior parietal cortex - RH | Piriform cortex - LH | 3.67 |
| Posterior parietal cortex - RH | Posterior parietal cortex - LH | 3.82 |
| Posterior parietal cortex - RH | Nucleus accumbens core - RH | 3.85 |
| Posterior parietal cortex - RH | Anterior cingulate cortex - RH | 3.86 |
| Posterior parietal cortex - RH | Piriform Cortex - RH | 3.75 |
| Posterior parietal cortex - RH | Amygdala - RH | 3.96 |
| Posterior parietal cortex - RH | Hippocampus - RH | 3.50 |