Table 2. The effects of ERK1/2 inhibitors in PMA-administrated THP-1 cells.
control | PD98059 | PMA administration for 5 days |
||
---|---|---|---|---|
— | PD98059 | |||
G0/G1 phase | 19.6 ± 2.8% | 20.5 ± 3.1% | 70.3 ± 2.9%* | 40.9 ± 5.4%*† |
S phase | 58.9 ± 6.2% | 60.1 ± 7.5% | 8.9 ± 3.1%* | 15.9 ± 2.8%*† |
G2/M phase | 16.2 ± 8.8% | 15.7 ± 6.8% | 10.6 ± 0.8%* | 43.2 ± 5.1%* |
(n = 5). PD98059, ERK1/2 inhibitor. *p < 0.05 compared to control group; †p < 0.05 compared to PMA-administrated group.