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. 2015 Jun;15(2):177–185.

Table 4.

Adjusted calculated* results according to body weight for antidepressant users and non-users by BMD site (g/cm2).

Multivariable model 1 Final model

BMD (g/cm2) BMD (g/cm2)

BMD site Non-users Users diff %a Non-users Users diff %a
Forearm
 60 kg 0.360 0.289 -19.7 0.266 0.245 -7.9
 70 kg 0.370 0.309 -16.5 0.276 0.275 -0.4
 80 kg 0.380 0.329 -13.4 0.286 0.305 6.6
 90 kg 0.390 0.349 -10.5 0.296 0.335 13.2
 100 kg 0.400 0.369 -7.7 0.306 0.365 19.3
 110 kg 0.410 0.389 -5.1 0.316 0.395 25.0
Lumbar spine
 60 kg 0.985 0.839 -14.8 1.103 1.010 -8.4
 70 kg 1.015 0.899 -11.4 1.123 1.070 -4.7
 80 kg 1.045 0.959 -8.2 1.143 1.130 -1.1
 90 kg 1.075 1.019 -5.2 1.163 1.190 2.3
 100 kg 1.105 1.079 -2.4 1.183 1.250 5.7
 110 kg 1.135 1.139 0.4 1.203 1.310 8.9
Total hip
 60 kg 0.989 0.831 -16.0 0.948 0.774 -18.4
 70 kg 1.029 0.911 -11.5 0.988 0.854 -13.6
 80 kg 1.069 0.991 -7.3 1.028 0.934 -9.1
 90 kg 1.109 1.071 -3.4 1.068 1.014 -5.1
 100 kg 1.149 1.151 0.2 1.108 1.094 -1.3
 110 kg 1.189 1.231 3.5 1.148 1.174 2.3
Total body
 60 kg 1.181 1.072 -9.2 1.120 1.059 -5.4
 70 kg 1.221 1.132 -7.3 1.160 1.129 -2.7
 80 kg 1.261 1.192 -5.5 1.200 1.199 -0.1
 90 kg 1.301 1.252 -3.8 1.240 1.269 2.3
 100 kg 1.341 1.312 -2.2 1.280 1.339 4.6
 110 kg 1.381 1.372 -0.7 1.320 1.409 6.7

Abbreviations: BMD, bone mineral density. Notes: Multivariable model 1 is adjusted for age and weight. Final model is adjusted for age, weight, height, nutritional calcium intake, MDD status, current use of bisphosphonates and calcium or vitamin D supplements.

*

from linear regression;

a

% difference when comparing the BMD of antidepressant users to non-users (calculated as follows BMDusers-BMDnon-users/BMDnon-users*100%).