Table 4.
Adjusted calculated* results according to body weight for antidepressant users and non-users by BMD site (g/cm2).
Multivariable model 1 | Final model | |||||
---|---|---|---|---|---|---|
BMD (g/cm2) | BMD (g/cm2) | |||||
BMD site | Non-users | Users | diff %a | Non-users | Users | diff %a |
Forearm | ||||||
60 kg | 0.360 | 0.289 | -19.7 | 0.266 | 0.245 | -7.9 |
70 kg | 0.370 | 0.309 | -16.5 | 0.276 | 0.275 | -0.4 |
80 kg | 0.380 | 0.329 | -13.4 | 0.286 | 0.305 | 6.6 |
90 kg | 0.390 | 0.349 | -10.5 | 0.296 | 0.335 | 13.2 |
100 kg | 0.400 | 0.369 | -7.7 | 0.306 | 0.365 | 19.3 |
110 kg | 0.410 | 0.389 | -5.1 | 0.316 | 0.395 | 25.0 |
Lumbar spine | ||||||
60 kg | 0.985 | 0.839 | -14.8 | 1.103 | 1.010 | -8.4 |
70 kg | 1.015 | 0.899 | -11.4 | 1.123 | 1.070 | -4.7 |
80 kg | 1.045 | 0.959 | -8.2 | 1.143 | 1.130 | -1.1 |
90 kg | 1.075 | 1.019 | -5.2 | 1.163 | 1.190 | 2.3 |
100 kg | 1.105 | 1.079 | -2.4 | 1.183 | 1.250 | 5.7 |
110 kg | 1.135 | 1.139 | 0.4 | 1.203 | 1.310 | 8.9 |
Total hip | ||||||
60 kg | 0.989 | 0.831 | -16.0 | 0.948 | 0.774 | -18.4 |
70 kg | 1.029 | 0.911 | -11.5 | 0.988 | 0.854 | -13.6 |
80 kg | 1.069 | 0.991 | -7.3 | 1.028 | 0.934 | -9.1 |
90 kg | 1.109 | 1.071 | -3.4 | 1.068 | 1.014 | -5.1 |
100 kg | 1.149 | 1.151 | 0.2 | 1.108 | 1.094 | -1.3 |
110 kg | 1.189 | 1.231 | 3.5 | 1.148 | 1.174 | 2.3 |
Total body | ||||||
60 kg | 1.181 | 1.072 | -9.2 | 1.120 | 1.059 | -5.4 |
70 kg | 1.221 | 1.132 | -7.3 | 1.160 | 1.129 | -2.7 |
80 kg | 1.261 | 1.192 | -5.5 | 1.200 | 1.199 | -0.1 |
90 kg | 1.301 | 1.252 | -3.8 | 1.240 | 1.269 | 2.3 |
100 kg | 1.341 | 1.312 | -2.2 | 1.280 | 1.339 | 4.6 |
110 kg | 1.381 | 1.372 | -0.7 | 1.320 | 1.409 | 6.7 |
Abbreviations: BMD, bone mineral density. Notes: Multivariable model 1 is adjusted for age and weight. Final model is adjusted for age, weight, height, nutritional calcium intake, MDD status, current use of bisphosphonates and calcium or vitamin D supplements.
from linear regression;
% difference when comparing the BMD of antidepressant users to non-users (calculated as follows BMDusers-BMDnon-users/BMDnon-users*100%).