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The TMPRSS2:ERG fusion gene and its most frequent transcripts. The most frequent transcripts of the TMPRSS2:ERG fusion gene consist in the fusion of exon 1 of TMPRSS2 to either exon 2 or 4 of ERG (T1-E4 or T1-E2). These transcripts encode for N-terminal truncated ERG proteins. Exon 1 from TPRSS2 is non-codifying. Transcription of the gene TMPRSS2 can start not only from its first exon, exon 1, but also from an alternative first exon (exon 0).
