Figure 4.
Circadian rhythm governs the response of gut bacterial composition shift to irradiation. (A–C) The number of observed species of enteric bacteria in mice housed in 8 h dark/16 h light (A), 12 h dark/12 h light (B), and 16 h dark/8 h light (C) cycles was assessed using 16S RNA sequencing, n = 3 per group; (D–F) The relative abundance of the top 10 bacteria at the phylum level in mice housed in 8 h dark/16 h light (D), 12 h dark/12 h light (E), and 16 h dark/8 h light (F) cycles was measured using 16S RNA sequencing, n = 3 per group. Statistically significant differences are indicated: Wilcoxon rank sum test.