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. 2016 Oct 31;17(11):1818. doi: 10.3390/ijms17111818

Figure 2.

Figure 2

Schematic representation of a metal complex interacting with DNA, resulting in elongation of the double-helix (left, sourced from Protein Data Bank (PDB) file 2MG8 [9] with metal complex inserted manually) and cisplatin covalently binding to DNA, causing the double helix to bend (right, sourced from PDB 1AIO) [10]. Central DNA figure sourced from PDB file 1D86 [11]. Oxygen is orange, phosphorous is yellow, carbon is cream/white and nitrogen is blue/purple. The base pairs are also represented as blue/purple rectangular panels.