Figure 5.
General structure of platinum complexes incorporating acridine and benz[c]acridine (left) and the acridine complex [PtCl(en)(1-{2-(acridin-9-ylamino)ethyl}-1,3-dimethylthiourea)](NO3)2 bound to DNA, as determined through a solution structure (PDB 1XRW) [39]. Counter-ions have been omitted for clarity and en = ethylenediamine. Oxygen is orange, phosphorous is yellow, carbon is cream/white and nitrogen is blue/purple. The base pairs are also represented as blue/purple rectangular panels.