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In vitro cytotoxicity of Pt7, Pt7’, Pt8 and Pt8’ against human NSCLC cell lines and HL-60 leukaemia cells. Values taken from references [34,38].
| Complex | IC50 (µM) | ||||
|---|---|---|---|---|---|
| Cell Line | |||||
| NCI-H460 | NCI-H520 | NCI-H522 | A549 | HL-60 | |
| Pt7 | 0.0052 ± 0.0001 | 0.043 ± 0.004 | 0.010 ± 0.001 | 0.0065 ± 0.0002 | – |
| Pt7’ | – | – | – | – | 0.13 |
| Pt8 | 0.24 ± 0.01 | 0.52 ± 0.01 | 0.12 ± 0.02 | 0.32 ± 0.06 | – |
| Pt8’ | 2.4 ± 0.5 | 2.2 ± 0.1 | 3.62 ± 0.08 | 12.4 ± 0.9 | – |
