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Cell survival fraction of Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) (A) and P. gingivalis (B) biofilms in a 3D gingival model after incubation with F-2 for 0.5 h, and subjected to various doses of light illumination from four sides. After PDI, biofilm maintained contact with F-2 for 0.5 h (☐) and 2 h (■) prior to plate count. Each value is the mean of three independent experiments ± standard deviation. * p < 0.05.
