Figure 1.

Effect of HCD-feeding (SD, standard diet; HCD, high carbohydrate diet) on weight and survival of Bcs1l^G/G mice. (A) Weight curves of homozygous (GG) and control (CO) mice on respective diets from weaning to deterioration stage (n = 4–8/group). Significant differences (p < 0.05) are shown for comparing CO on SD with CO on HCD (*) and GG on SD (δ); and CO on HCD with GG on HCD (Φ), Tukey’s multiple comparison; (B) survival curve of homozygous mice (GG) on SD (n = 30) and HCD (n = 21). Median survival was 33 days on SD, 29 days on HCD (p < 0.0001, Log-rank, Mental-Cox test).