. 2016 Nov 5;17(11):1845. doi: 10.3390/ijms17111845

Table 1.

Correlation of CK7, ELF3, EGFR, EphB4 expression in tissues with NSCLC’s clinicopathological characteristics.

Clinicopathological Parameters		N	CK7		ELF3		EGFR		EphB4
Clinicopathological Parameters		N	Mean ± SD	p-Value	Mean ± SD	p-Value	Mean ± SD	p-Value	Mean ± SD	p-Value
Gender	Male	79	36.73 ± 19.44	0.608	36.64 ± 19.60	0.330	35.23 ± 20.76	0.590	32.98 ± 19.65	0.571
Gender	Female	32	34.60 ± 29.66	0.608	32.59 ± 20.20	0.330	32.84 ± 21.87	0.590	30.64 ± 19.76	0.571
Age (year)	<60	46	36.54 ± 18.05	0.852	36.24 ± 18.25	0.728	36.58 ± 20.62	0.393	34.41 ± 19.20	0.345
Age (year)	≥60	65	35.82 ± 20.96	0.852	34.93 ± 20.89	0.728	33.10 ± 21.33	0.393	30.82 ± 19.92	0.345
Smoking history	No	46	36.27 ± 21.05	0.947	34.45 ± 20.20	0.646	34.08 ± 20.61	0.847	32.84 ± 19.78	0.812
Smoking history	Yes	65	36.01 ± 18.90	0.947	36.21 ± 19.57	0.646	34.87 ± 21.45	0.847	31.93 ± 19.65	0.812
Lesion site	Left lobe	50	34.45 ± 17.73	0.413	34.92 ± 19.38	0.790	33.65 ± 20.14	0.686	31.78 ± 18.85	0.797
Lesion site	Right lobe	61	37.49 ± 21.27	0.413	35.93 ± 20.22	0.790	35.28 ± 21.85	0.686	32.74 ± 20.37	0.797
Histopathological type	SCC	46	34.46 ± 18.00	0.460	35.14 ± 19.34	0.879	32.67 ± 19.35	0.423	31.03 ± 19.23	0.567
Histopathological type	ADC	65	37.29 ± 20.92	0.460	35.72 ± 20.21	0.879	35.86 ± 22.17	0.423	33.21 ± 19.99	0.567
Tumor size	≤3 cm	24	37.47 ± 22.02	0.727	35.88 ± 20.95	0.938	36.82 ± 24.34	0.615	30.90 ± 18.19	0.653
Tumor size	>3 cm	86	35.86 ± 19.25	0.727	35.52 ± 19.61	0.938	34.07 ± 20.18	0.615	32.94 ± 20.08	0.653
Differentiation	Well/Moderate	86	34.84 ± 19.72	0.207	34.09 ± 19.47	0.173	33.23 ± 21.31	0.224	30.56 ± 19.60	0.082
Differentiation	Poor	25	40.51 ± 19.51	0.207	40.23 ± 20.42	0.173	39.05 ± 19.73	0.224	38.32 ± 18.81	0.082
T stage	T2	94	35.55 ± 19.70	0.476	34.63 ± 19.68	0.289	33.33 ± 20.89	0.153	30.78 ± 19.18	0.053
T stage	T3	17	39.27 ± 20.16	0.476	40.18 ± 20.14	0.289	41.27 ± 21.08	0.153	40.77 ± 20.45	0.053
Lymph node status	N0	18	31.75 ± 13.75	0.188	30.02 ± 13.90	0.105	30.47 ± 15.85	0.275	28.47 ± 15.94	0.296
Lymph node status	N1–3	93	36.96 ± 20.64	0.188	36.53 ± 20.60	0.105	35.33 ± 21.86	0.275	33.05 ± 20.24	0.296
Distant metastasis	M0	109	36.20 ± 19.85	0.735	35.56 ± 19.87	0.748	34.64 ± 21.12	0.721	32.39 ± 19.67	0.745
Distant metastasis	M1	2	31.40 ± 14.85	0.735	31.00 ± 16.69	0.748	29.25 ± 18.31	0.721	27.80 ± 22.49	0.745
Clinical stage	I/II	56	28.13 ± 12.80	1.06 × 10⁻⁵	27.09 ± 13.95	3.23 × 10⁻⁶	25.14 ± 15.18	7.62 × 10⁻⁷	23.87 ± 14.95	2.05 × 10⁻⁶
Clinical stage	III/IV	55	44.25 ± 22.18	1.06 × 10⁻⁵	44.01 ± 21.22	3.23 × 10⁻⁶	44.11 ± 21.91	7.62 × 10⁻⁷	40.90 ± 20.18	2.05 × 10⁻⁶

SCC: squamous cell carcinoma; ADC: adenocarcinoma; Mean: mean value of relative expression; SD: standard deviation; Numbers in bold: p < 0.05.