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. 2016 Nov 10;17(11):1857. doi: 10.3390/ijms17111857

Table 1.

Hub nodes and large BC nodes.

Parameters Gene Name
(Hub + Large BC) nodes AR, DAZAP2, ESR1
Hub nodes PRMT1, ATXN1, UBB, KHDRBS3, DAZ1, RBM9, PUM2, QKI, EGFR
Large BC nodes RB1, NR3C1, SMAD3, EP300, JUN, HDAC1, SMAD4, MAPK1, SP1, CREBBP, BCRA1, RELA

The highly connected nodes known as hubs are more important than lesser connected nodes and the nodes with large Betweenness Centrality (BC) values are bottleneck proteins within a scale-free network; AR, DAZAP2, and ESR1 are hub nodes that have a large BC.