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. 2016 Nov 18;17(11):1859. doi: 10.3390/ijms17111859

Figure 5.

Figure 5

Regulation effect of overexpressing CAPON-S on the Akt and mTOR signaling. (A,B) Antibody array was used to screen important signaling molecules in Vector and CAPON-S U87 glioma cells. Representative spot pictures are shown in (A); PC, positive control; NC, negative control. The spot intensities of those molecules with significant changes, such as p-Akt (Thr308), p-Akt (Ser473), and p-mTOR (Ser2448), are shown in (B); (C,D) Western blot was used to confirm the antibody array data in Vector and CAPON-S U87 glioma cells; Representative blot pictures are shown in (C); Quantitative graphs for the relative protein levels normalized to Actin are shown in (D). (* p < 0.05; ** p < 0.01; *** p < 0.001).