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. 2016 Nov 22;17(11):1944. doi: 10.3390/ijms17111944

Figure 2.

Figure 2

Examples of DAT, D1 and D2 receptors binding in the adult rat brain following childhood/adolescent APD treatment. (A–D) The schematic diagram adapted from a rat brain atlas [42] showing the level of Bregma for each investigated region ((A) PFC: 4.68 mm; (B) CPu & NAc: 1.08 mm; (C) Hippocampus: −2.76 mm; (D) SN & VTA: −4.92 mm). (A’–D’) Examples of autoradiograms to demonstrate [3H]WIN35428 binding to DAT; (A”–D”) Examples of autoradiograms to demonstrate [3H]SCH23390 binding to DA D1 receptors (D1R); (A’’’–D’’’) Examples of autoradiograms to demonstrate [3H]Raclopride to DA D2 receptors (D2R). APD: Antipsychotic drug; CPu: Caudate Putamen; DA: Dopamine; DAT: Dopamine Active Transporter; Hipp: Hippocampus; NAc: Nucleus Accumbens; PFC: Prefrontal cortex; SN: Substantia Nigra; VTA: Ventral Tegmental Area.