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. 2016 Nov 23;17(11):1961. doi: 10.3390/ijms17111961

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Reduction of collagen fibers and delayed re-epithelialization in Hmgb1^+/− wound on Day 3 after wound surgery. (A) Sections were stained with Mallory’s azan. Representative palatal wound sections show the collagen bundles of WT and Hmgb1^+/− mice. Note that blue indicates collagen bundle stained by Mallory’s azan stain. Arrows indicate weave-like pattern of collagen bundles in Hmgb1^+/− mice. Original magnifications: left panels 200×, right panels 400×; (B) Sections were stained with hematoxylin and eosin. E, epithelium; C, collagen bundle; P, palatal bone. n = 5 wounds for each time point and genotype.