Table 1. Relationship between miR-590-5p expression and clinicopathologic features of CRC patients (n=60).
Variable |
Relative miR-590-5p expression |
P-value | |
---|---|---|---|
Low (n=30) | High (n=30) | ||
Gender | NS | ||
Women | 12 | 14 | |
man | 18 | 16 | |
Age | NS | ||
<60 | 13 | 15 | |
≥60 | 17 | 15 | |
Primary tumor sites | NS | ||
Ascending colon | 4 | 7 | |
Transverse colon | 2 | 1 | |
Descending colon | 4 | 3 | |
Sigmoid colon | 8 | 9 | |
Rectum | 12 | 10 | |
Histological differentiation | NS | ||
Well | 8 | 6 | |
Moderate | 17 | 18 | |
Poor | 5 | 6 | |
Tumor size | <0.01 | ||
<5 cm | 3 | 25 | |
≥5 cm | 27 | 5 | |
Lymph node metastasis | <0.01 | ||
Yes | 26 | 9 | |
No | 4 | 21 | |
Distant metastasis | NS | ||
Yes | 10 | 5 | |
No | 20 | 25 | |
Tumor stage | <0.01 | ||
I–II | 4 | 19 | |
III–IV | 26 | 11 |
Note: CRC patients were divided into miR-590-5p ‘High' group (relative fold change of ‘low' group) and ‘Low' group according to the staining by in situ hybridization. NS, not significant between any groups. Differences among variables were assessed by χ2 or Fisher's exact χ2-test