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. 2016 Oct 13;7(10):e2415. doi: 10.1038/cddis.2016.333

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Copyright © 2016 The Author(s)

Cell Death and Disease is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Clinical relevance of CDK5–ERK5–AP-1 axis in human CRC. (a) Western blotting analysis of CDK5, p-ERK5 (Thr732), c-jun and c-fos in nine fresh human CRC samples(T1–T9); β-actin and total ERK5 were used as loading controls. (b) Correlation analysis were shown by Spearman's correlation analyses between CDK5 expression and p-ERK5, c-jun and c-fos