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. 2016 Dec 1;17:80. doi: 10.1186/s12868-016-0314-3

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Microarray analysis indicates that rhBMP-2 induces many genes involved in neuroinflammation in the DRG. Heat map showing genes whose expression was altered at 1, 3 and 7 dps in the ipsilateral L4/L5 DRGs of rhBMP-2/ACS or vehicle/ACS implanted rats. Blue color intensity indicates decreasing transcript expression as compared to the mean value across all samples. Red color intensity indicates increasing transcript expression as compared to the mean value across all samples. The green outlined panel indicates high significant differences at 3 dpi. Each column represents data from RNA extracted from one rat