Table 4.
Risk factor | Category | AD cohort | Non-AD cohort | ||||
---|---|---|---|---|---|---|---|
Mortality/ 100 PY | Unadjusted HR (95% CI) |
Adjusted HRa
(95% CI) |
Mortality/ 100 PY | Unadjusted HR (95% CI) |
Adjusted HRa
(95% CI) |
||
Age at baseline, increase per year | 1.04 (1.03–1.05) | 1.05 (1.05–1.06) | N.A | 1.07 (1.06–1.09) | 1.08 (1.07–1.10) | ||
Sex | Men | 25.1 | 1.00 (reference) | 1.00 (reference) | 19.4 | 1.00 (reference) | 1.00 (reference) |
Women | 47.7 | 1.90 (1.74–2.08) | 2.09 (1.90–2.29) | 39.3 | 2.06 (1.79–2.36) | 2.43 (2.10–2.80) | |
Highest occupational social class before follow-up | Managerial/professional | 29.9 | 1.00 (reference) | 1.00 (reference) | 23.4 | 1.00 (reference) | N.A |
Office worker | 25.6 | 0.85 (0.72–1.01) | 1.02 (0.86–1.21) | 20.7 | 0.88 (0.66–1.16) | ||
Farming/forestry | 30.6 | 1.02 (0.89–1.17) | 1.01 (0.88–1.15) | 23.0 | 0.97 (0.78–1.21) | ||
Sales/industry/cleaning | 29.6 | 0.99 (0.88–1.11) | 1.05 (0.93–1.18) | 23.7 | 1.00 (0.83–1.22) | ||
Unknown | 28.8 | 0.96 (0.83–1.12) | 1.04 (0.89–1.21) | 24.5 | 1.05 (0.82–1.34) | ||
Did not respond | 25.7 | 0.86 (0.55–1.33) | 1.03 (0.67–1.61) | 23.3 | 0.97 (0.48–1.98) | ||
Hip replacement | No | 29.36 | 1.00 (reference) | 1.00 (reference) | 23.38 | 1.00 (reference) | 1.00 (reference) |
Yes | 21.85 | 0.74 (0.49–1.13) | 0.68 (0.45–1.04) | 20.36 | 0.86 (0.46–1.61) | 1.22 (0.65–2.29) | |
Knee replacement | No | 29.62 | 1.00 (reference) | 1.00 (reference) | 23.47 | 1.00 (reference) | 1.00 (reference) |
Yes | 19.88 | 0.67 (0.52–0.87) | 0.73 (0.56–0.95) | 18.83 | 0.80 (0.51–1.24) | 0.88 (0.56–1.38) | |
Cardiovascular disease | No | 26.5 | 1.00 (reference) | 1.00 (reference) | 20.2 | 1.00 (reference) | 1.00 (reference) |
Yes | 32.1 | 1.21 (1.12–1.32) | 1.19 (1.10–1.29) | 26.0 | 1.28 (1.12–1.47) | 1.31 (1.15–1.50) | |
Stroke | No | 28.7 | 1.00 (reference) | 1.00 (reference) | 22.3 | 1.00 (reference) | 1.00 (reference) |
Yes | 36.8 | 1.28 (1.12–1.47) | 1.19 (1.03–1.37) | 37.9 | 1.70 (1.38–2.09) | 1.67 (1.35–2.06) | |
Diabetes | No | 28.7 | 1.00 (reference) | 1.00 (reference) | 23.3 | 1.00 (reference) | 1.00 (reference) |
Yes | 33.3 | 1.16 (1.03–1.31) | 1.22 (1.08–1.38) | 23.9 | 1.03 (0.85–1.24) | 1.17 (0.96–1.42) | |
Asthma/COPD | No | 28.9 | 1.00 (reference) | 1.00 (reference) | 23.5 | 1.00 (reference) | 1.00 (reference) |
Yes | 33.4 | 1.16 (1.01–1.33) | 1.17 (1.02–1.34) | 22.2 | 0.93 (0.74–1.17) | 1.04 (0.83–1.31) | |
Cancer treatment | No | 29.3 | 1.00 (reference) | 1.00 (reference) | 23.3 | 1.00 (reference) | 1.00 (reference) |
Yes | 23.6 | 0.81 (0.52–1.24) | 0.88 (0.57–1.35) | 26.4 | 1.12 (0.68–1.83) | 1.63 (0.99–2.68) | |
Any mental or behavioural disorder | No | 28.2 | 1.00 (reference) | 1.00 (reference) | 22.8 | 1.00 (reference) | 1.00 (reference) |
Yes | 31.6 | 1.12 (1.03–1.22) | 1.18 (1.08–1.29) | 28.1 | 1.25 (1.02–1.54) | 1.28 (1.04–1.58) |
aAdjusted for occupational social class