Table 1.
Summary of cell death in monoculture, neuroglial mixed culture and brain slices
| Cell death | Monoculturea | Mixed cultureb | Brain slicesc | |
|---|---|---|---|---|
| Mouse AST | HC | No death | No death | No death |
| #53+HC | 33.9 ± 1.5% | 32.0 ± 1.7% | Damage from 8 h | |
| Mouse N | HC | 93.4 ± 4.0% | 31.4 ± 4.0% | 17.4 ± 0.7% |
| #53+HC | 97.7 ± 2.1% | 72.3 ± 11.1% | 52.3 ± 2.7% | |
| Mouse OL | HC | 70.8 ± 2.8% | 56.0 ± 1.4% | 26.4 ± 5.7% |
| #53+HC | 61.3 ± 7.8% | 73.2 ± 5.4% | 43.7 ± 3.9% | |
| Mouse OPC | HC | 42.2 ± 5.6% | No death | No death |
| #53+HC | 36.9 ± 5.6% | No death | 46.9 ± 16.9% | |
Abbreviations: AST astrocyte, N neuron, OL mature oligodendrocyte, OPC oligodendrocyte precursor cell, HC human complement, #53+HC rAb #53 plus human complement.
aPercentage of cell death at 4 h
bPercentage death at 4 h except neuron (N) death with #53+HC which was maximal at 1.5 h
cCell death in brain slices at 48 h