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. 2016 Oct 17;594(23):7105–7126. doi: 10.1113/JP272979

Figure 11. Quantitative mRNA expression of HCN4 and ANP in the SAN and right atrium .

Figure 11

A and B, expression of HCN4 (A) and ANP (B) in the right atrium and SAN of young and aged hearts. * P < 0.05 vs. young; + P < 0.05 vs. right atrium by two‐way ANOVA with Tukey's post hoc test; n = 9 young and 8 aged hearts. These data confirm that samples used for qPCR experiments and histology were from the SAN based on the high expression of HCN4 and low expression of ANP in the SAN compared to the right atrium.