Table 1.
Demographic and characteristics of CSU activity
| Total sample size, n = 139 1 | |
|---|---|
| Female/Male, n (%) | 96 (69.1)/43 (30.9) |
| IgE (range in kU/L), mean ± SD | 145.38 ± 150 (1.3–909) |
| Age (y), mean ± SD | 45.5 ± 14.7 |
| Thyroid disease, n (%) | 23/101 (22.8) |
| Autoimmunity, n (%) | 19/23 (82.6) |
| Subclinic disease, n (%) | 11/19 (57.9) |
| Hypothyroidism, n (%) | 7/19 (36.8) |
| Hyperthyroidism, n (%) | 1/19 (5.3) |
| Groups by ASST/CD63 results | |
| ASST +/ CD63 + subgroup (n = 25), mean ± SD (range) | |
| UAS 4.26 ± 1.84 (1–7) | |
| UAS7 26.57 ± 10.56 (7–42) | |
| UAS3w 61.87 ± 25.62 (21–120) | |
| ASST +/ CD63‐ subgroup (n = 54), mean ± SD | |
| UAS 2.92 ± 1.75 (0–6) | |
| UAS7 18.40 ± 12.05 (0–49) | |
| UAS3w 39.88 ± 25.44 (10–120) | |
| ASST‐/CD63‐ subgroup (n = 59), mean ± SD | |
| UAS 2.93 ± 2.22 (0–12) | |
| UAS7 17.28 ± 12.61 (0–48) | |
| UAS3w 38.39 ± 28.59 (15–120) | |
ASST, autologous serum skin test; CD63, basophil activation test; SD, standard deviation; UAS, Urticaria Activity Score/the day before; UAS7, Urticaria Activity Score the week before; UAS3w, Urticaria Activity Score 3 weeks before; y, years.
From the 139 patients with ASST performed, the UAS was not available in nine patients. And one patient showed negative ASST and positive CD63.
CSU Categorical Health States attending the UAS7 results: no urticaria (UAS 7 = 0), well controlled activity (UAS7: 1–6), mild activity (UAS7: 7–16), moderate activity (UAS7:17–27), severe activity (UAS7: 28–42) 20.
1
One patient showed positive CD63 and negative ASST.