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. 2016 Dec 1;594(23):6969–6985. doi: 10.1113/JP271903

Table 6.

Effect of age and exercise training on heart and liver markers of oxidative stress and antioxidants

Marker Y‐ApoE‐UT O‐ApoE‐UT O‐ApoE‐ExT O‐C57‐UT O‐C57‐ExT
AOPP in heart (μmol mg−1) 28.5 ± 2.4 75.3 ± 5.8* 68.4 ± 5.6*† 152.7 ± 14.4 138.9 ± 6.1
Catalase in heart (μmol min−1 mg−1) 831 ± 76 2492 ± 436* 2033 ± 400*† 4955 ± 508 4266 ± 449
GPX in heart (μmol min−1 mg−1) 451 ± 11 322.7 ± 7* 338 ± 7* 834 ± 87 781 ± 83
SOD in heart (μmol min−1 mg−1) 32.7 ± 4.5 24.1 ± 2.8* 32.2 ± 2.4 48.0 ± 6.6 44.9 ± 7.9
AOPP in liver (μmol mg−1) 14.8 ± 5.3 41.4 ± 10.9* 36.0 ± 9.1*† 6.6 ± 2.0 9.3 ± 3.4
MDA in liver (μmol mg−1) 0.75 ± 0.42 4.11 ± 2.08* 2.37 ± 1.42*† 1.87 ± 0.45 2.37 ± 1.47
SOD in liver μmol min−1 mg−1) 0.92 ± 0.12 0.71 ± 0.26 0.83 ± 0.13 0.75 ± 0.24 0.79 ± 0.21
GPX in liver μmol min−1 mg−1) 14.8 ± 12.9 6.0 ± 4.5* 27.4 ± 9.6*† 10.9 ± 1.5 22.7 ± 6.6

Abbreviations: AOPP, protein oxidation; FRAP, ferric reducing antioxidant power; GPX, catalase and SOD, antioxidant enzymes activities; and MDA, malondialdehyde. Groups are as in Table 2. *Significantly different (P < 0.05) from young. Significantly different (P < 0.05) from corresponding untrained. Significantly different (P < 0.05) from corresponding ApoE−/−.