TABLE 2.
Univariate Analysis of Risk Factors for Relapse in Pediatric Patients With Ovarian Immature Teratomas (n = 98)
| Patient Characteristic | Level | No. of Events/No. of Patients | Estimated HR (95% CI) | Pa |
|---|---|---|---|---|
| Age | ≥11 y | 7/49 | 3.76 (0.78–18.10) | .076 |
| <11 y | 2/49 | — | ||
| Stage | III | 7/27 | 10.32 (2.14–49.68) | .0003 |
| I/II | 2/71 | — | ||
| Grade | 3 | 8/38 | —b | .0006 |
| 1/2 | 0/50 | — | ||
| AFP at presentation | High | 5/44 | 1.78 (0.43–7.44) | .42 |
| Normal | 3/45 | — | ||
| Treatment | Chemotherapy | 3/8 | 6.61 (1.65–26.45) | .002 |
| Surgery | 6/90 | — |
Abbreviations: AFP, α-fetoprotein; CI, confidence interval; HR, hazard ratio.
a
From the log-rank test.
b
The HR could not be estimated because there was no event for grade 1/2.