Table 1.
Characteristics of the study population according to plaque presence and size
| (N=954) | No Plaque N=296 |
Small Plaque N=543 |
Large plaque N=115 |
P |
|---|---|---|---|---|
| Age (years) | 68.4 ± 9.0 | 72.3 ± 9.0 | 76.8 ± 8.2 | <0.001 |
| Male, n (%) | 97(32.8) | 222(40.9) | 32 (27.8) | 0.007 |
| Race-Ethnicity | ||||
| White, n (%) | 30 (10.1) | 83 (15.3) | 21 (18.3) | |
| Hispanic, n (%) | 210 (71.0) | 365 (67.2) | 75 (65.2) | 0.173 |
| Black, n (%) | 48 (16.2) | 82 (15.1) | 19 (16.5) | |
| Other, n (%) | 8 (2.7) | 13 (2.4) | 0 (0) | |
| Body mass index, kg/m2 | 29.4 ± 5.0 | 27.7 ± 4.7 | 28.0 ± 5.0 | <0.001 |
| Hypertension, n (%) | 220 (74.3) | 436 (80.3) | 102 (88.7) | 0.004 |
| Hypercholesterolemia, n (%) | 198 (66.9) | 365 (67.2) | 87 (76.7) | 0.182 |
| Diabetes mellitus, n (%) | 93 (31.4) | 162 (29.8) | 28 (24.4) | 0.368 |
| Coronary Artery Disease, n (%) | 11 (3.7) | 35 (6.5) | 11 (9.6) | 0.063 |
| History of MI, n (%) | 10 (3.4) | 28 (5.2) | 7 (6.1) | 0.388 |
| History of AF, n (%) | 17 (5.7) | 32 (5.9) | 11 (9.6) | 0.303 |
| Smoking history, n (%) | 141 (47.6) | 292 (53.8) | 70 (60.9) | 0.041 |
| Hypertension medication, n (%) | 198 (66.9) | 398 (73.3) | 94 (81.7) | 0.008 |
| SBI, n (%) | 26 (9.6) | 81 (15.6) | 22 (19.1) | 0.02 |
| WMHV/total cranial volume (%) | 0.44 ± 0.48 | 0.69 ± 0.86 | 0.98 ± 1.13 | <0.001 |
SBI=silent brain infarct
WMHV=white matter hyperintensity volume
MI=myocardial infarction
AF=atrial fibrillation