Table 3.

Association of AAP with SBI and WMHV in the upper quartile (WMHV-Q4)

	SBI		WMHV-Q4
	Unadjusted OR (95% CI)	Adjusted OR* (95% CI)	Unadjusted OR (95% CI)	Adjusted OR* (95% CI)
AAP thickness (mm)	1.19 (1.05–1.35)†	1.08 (0.94–1.23)	1.34 (1.21–1.49)†	1.17 (1.04–1.32)†
AAP thickness category
No plaque	Reference	Reference	Reference	Reference
Small plaque (<4mm)	1.85 (1.18–2.90)†	1.47 (0.92–2.34)	2.02 (1.40–2.91)†	1.49 (0.10–2.23)
Large plaque (≥ 4 mm)	2.26 (1.24–4.15)†	1.46 (0.77–2.77)	3.49 (2.14–5.70)†	1.79 (1.04–3.09)‡

AAP=aortic arch plaque

SBI=silent brain infarct

WMHV=white matter hyperintensity volume

Values in tables are odds ratios (OR) and 95% confidence intervals (CI)

^*Adjusted for age, sex, hypertension, diabetes, history of atrial fibrillation, and hypertension medication in SBI analyses; and for age, race-ethnicity, hypertension, history of atrial fibrillation, body mass index, and hypertension medication in WMHV analyses.

^†P < 0.01

^‡P < 0.05