For the 59 scans that had stable lesion volume estimates with 90s scan duration, the vertical color-coding corresponds to the cumulative proportion of scans that have reached their optimal scan duration: 25% of scans have an optimal scan duration <29.5s; 75% <44s, and 100% <69s. These data indicate that, with a uniform T0 of 10s, a total scan duration of 69s would have been sufficient for all 59 cases. A total scan duration of 60s, would have been sufficient for 93% of the cases (55 of 59). The averaged VOF for the 59 cases, normalized to a T0 of 10s, is shown (blue curve) with its standard deviation (grey shaded area).