Table 2.
Not using HT | Currently using HT | ||||||||
---|---|---|---|---|---|---|---|---|---|
Cases | Person- years |
HRa | 95% CI | Cases | Person- years |
HRb | 95% CI | ||
Height (inches) | |||||||||
<63 | 59 | 103,432 | 1.0 | c | 131 | 128,704 | 1.0 | ||
63–66 | 188 | 285,585 | 1.29 | 0.96–1.73 | |||||
≥67 | 106 | 136,302 | 1.75 | 1.26–2.42 | 67 | 41,732 | 1.78 | 1.32–2.40 | |
missing | 1 | 1,256 | 0 | 305 | |||||
ptrend=0.0005 | |||||||||
BMI at age 18 (kg/m2) | |||||||||
<25 | 269 | 454,597 | 1.0 | 173 | 151,357 | 1.0 | |||
≥25 | 67 | 54,392 | 1.77 | 1.34–2.33 | 18 | 13,767 | 1.06 | 0.64–1.75 | |
missing | 18 | 17,586 | 7 | 5,616 | |||||
BMI at baseline (kg/m2) | |||||||||
<25 | 134 | 325,310 | 1.0 | 122 | 108,264 | 1.0 | |||
25–29 | 97 | 119.747 | 1.51 | 1.16–1.97 | 69 | 58,048 | 100 | 0.74–1.35 | |
≥30 | 110 | 67,501 | 2.67 | 2.04–3.50 | |||||
missing | 13 | 14,018 | 7 | 4,428 | |||||
ptrend<0.0001 | |||||||||
Weight change (pounds) (age 18 to baseline) |
|||||||||
loss ≥10 | 40 | 56,578 | 1.69 | 1.16–2.44 | 128 | 104,603 | 1.0 | ||
stable | 95 | 267,152 | 1.00 | ||||||
gain ≥25 | 203 | 185,307 | 2.20 | 1.72–2.83 | 62 | 60,519 | 0.83 | 0.61–1.13 | |
missing | 16 | 17,538 | 8 | 5,618 | |||||
Waist-to-height ratio | |||||||||
<0.48 | 65 | 195, 604 | 1.0 | 75 | 64,317 | 1.0 | |||
≥0.48 | 204 | 206,120 | 1.91 | 1.43–2.54 | 91 | 71,962 | 0.87 | 0.64–1.19 | |
missing | 85 | 124,852 | 32 | 34,461 |
Abbreviations: BMI: body mass index; CI: confidence interval; HR: hazard ratio; HT: hormone therapy.
Adjusted for the interaction between age at menarche and time-dependent age, gravidity, age at last pregnancy, duration of oral contraceptive use, the interaction between history of hypertension and time-dependent age, history of diabetes, and average daily caloric intake; age was the time metric and the model was stratified by age at baseline.
Adjusted for duration of oral contraceptive use, and the interaction between history of hypertension and time-dependent age; age was the time metric and the model was stratified by age at baseline.
Indicates cells which were collapsed for analysis.