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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Cancer Causes Control. 2016 Nov 1;27(12):1419–1428. doi: 10.1007/s10552-016-0820-8

Table 3.

Full models reflecting body size over the life-course and risk of type 1 endometrial cancer by HT use, California Teachers Study, 1995–2012.

Not using HT Currently using HT
Heighta BMI
(age 18)		 BMI
(baseline)		 Weight change Adiposity Cases HRb 95% CI Cases HRc 95% CI
Short Normal Normal Loss 3 1.96 0.55–6.94 67 1.0
Stable 12 1.0
Gain 2 1.62 0.36–7.23 4 0.47 0.17–1.29
Overweight/
obese		 Abdominal 19 2.35 1.14–4.85 31 1.07 0.69–1.65
Gluteal 0 1 0.49 0.07–3.55
Overweight/
obese		 Normal 4 2.88 0.93–8.95 6 1.17 0.50–2.70
Overweight/
obese		 Abdominal 5 3.93 1.38–11.22 6 1.62 0.70–3.77
Gluteal 0 0
Tall Normal Normal Loss 12 2.00 0.90–4.46 32 1.82 1.19–2.78
Stable 57 1.40 0.75–2.62
Gain 25 2.90 1.45–5.79 11 2.46 1.30–4.68
Overweight/
obese		 Abdominal 86 3.22 1.75–5.91 14 1.85 1.04–3.31
Gluteal 3 1.32 0.37–4.70 1 1.00 0.14–7.22
Overweight/
obese		 Normal 15 2.94 1.37–6.29 1 0.60 0.08–4.33
Overweight/
obese		 Abdominal 30 5.99 3.03–11.82 1 1.03 0.14–7.47
Gluteal 0 0

Abbreviations: BMI: body mass index; CI: confidence interval; HR: hazard ratio; HT: hormone therapy.

a

Body size cut-points: height <63,≥63 (for women not using HT) and <67,≥67 (for women currently using HT); BMI (age 18) and BMI (baseline) <25,≥25; weight change: loss >10 pounds, loss <10 pounds or gain <25 pounds (stable), gain ≥25 pounds (for women not using HT) and loss or gain <25 pounds, gain ≥25 pounds (for women currently using HT); adiposity ≥0.48 (abdominal),<0.48 (gluteal).

b

Adjusted for the interaction between age at menarche and time-dependent age, gravidity, age at last pregnancy, duration of oral contraceptive use, the interaction between history of hypertension and time-dependent age, history of diabetes, and average daily caloric intake; age was the time metric and the model was stratified by age at baseline.

c

Adjusted for duration of oral contraceptive use, and the interaction between history of hypertension and time-dependent age; age was the time metric and the model was stratified by age at baseline.