TABLE 4.

Characteristics of 99 Symptomatic Children <5 Years Old Newly Diagnosed With TB in 20 Jurisdictions in the United States in 2005–2006 and Enrolled in Observational Study, by the Child’s Nativity

Symptomatic Participant Characteristics	All Cases (N = 99)		US Born (N = 83)		Foreign Born (N = 16)		Risk Ratioa	95% CI
	n	% (n/N)	n	% (n/N)	n	% (n/N)
Cough
Yes	53	54	45	54	8	50	1.15	0.47–2.83
No	46	46	38	46	8	50	referent
Fever
Yes	55	56	51	61	4	25	3.75	1.30–10.82
No	44	44	32	39	12	75	referent
Night sweats
Yes	43	43	34	41	9	56	0.60	0.24–1.48
No	56	57	49	59	7	44	referent
Weight loss
Yes	38	38	33	40	5	31	1.37	0.52–3.64
No	61	62	50	60	11	69	referent
Lymphadenopathy
Yes	20	20	16	19	4	25	0.78	0.28–2.16
No	77	78	65	78	12	75	referent
Unknown	2	2	2	2	0	0	excluded
Reason for initially seeking health careb
Screenings and well-baby examinations	18	18	8	10	10	63	0.13	0.06–0.32
Symptoms	57	58	52	63	5	31	2.99	1.12–7.95
Contact investigation or known TB exposure	24	24	23	28	1	6	4.80	0.67–34.47
Median days from symptom onset to treatment initiation (IQR)	52	(23–117)	44.5	(21–112)	115	(36–160)	0.999	0.998–1.000
Median number of physician visits from symptom onset to treatment initiationc (IQR)	2	(1–3)	2	(1–2.5)	2	(1–3)	1.023	0.951–1.100

^aRisk ratio estimates the relative risk of US-born children compared with foreign-born children (with asymptotic 95% CIs).

^bReasons for initially seeking health care among symptomatic adopted children were post-adoption check-ups (n = 2), well-baby examinations, and symptoms (n = 1).

^cNumber of physician visits required for TB diagnosis for persons reporting symptoms.