Table 1. Clinical characteristics of PD patients with and without CI as diagnosed by 3MS.
| Total | CI group | No CI group | P | |
|---|---|---|---|---|
| (n = 445) | (n = 105) | (n = 340) | ||
| Age (years) | 51.3±14.2 | 57.5±12.2 | 49.4±14.3 | <0.001 |
| Male (%) | 233 (52.4%) | 45(42.9%) | 188(55.3%) | 0.026 |
| PD duration (months) | 25.1(11.1–49.1) | 24.0(9.5–47.7) | 25.9(11.1–49.6) | 0.442 |
| Primary kidney disease | ||||
| Diabetic nephropathy (%) | 89(20.%) | 29(27.8%) | 60(17.8%) | |
| Hypertensive nephropathy (%) | 59 (13.4%) | 19(18.2%) | 40(11.8%) | |
| Chronic glomerulonephritis (%) | 206 (46.7%) | 39(37.5%) | 107(31.7%) | |
| Other (%) | 87 (19.7%) | 17(16.3%) | 70(20.7%) | |
| DM (%) | 101 (22.7%) | 35(33.3%) | 66(19.4%) | 0.003 |
| Cardiovascular disease (%) | 92 (20.7%) | 31(29.5%) | 61(17.9%) | 0.01 |
| Charlson Index | 5 (3–8) | 5 (3–10) | 4(3–8) | 0.021 |
| Level of education | <0.001 | |||
| Elementary school or lower | 78 (17.5%) | 50(47.6%) | 28(8.2%) | |
| Middle school | 136 (30.6%) | 26(24.8%) | 110(32.4%) | |
| High school | 129 (29.0%) | 23(21.9%) | 106(31.2%) | |
| Above high school | 102 (22.9%) | 6(5.7%) | 96(28.2%) | |
| Body mass index (kg/m2) | 22.8±3.5 | 23.5±3.5 | 22.6±3.48 | 0.025 |
| Systolic blood pressure (mmHg) | 135.2±18.3 | 137.9±17.6 | 134.5±18.4 | 0.101 |
| Diastolic blood pressure (mmHg) | 82.1±12.3 | 79.6±10.9 | 82.7±12.6 | 0.046 |
| Hemoglobin (g/L) | 105.1±17.8 | 103.1±19.4 | 105.7±17.2 | 0.208 |
| Serum albumin (g/L) | 36.0±5.6 | 33.6±5.6 | 36.7±5.4 | <0.001 |
| Triglyceride (mmol/L) | 1.9±1.3 | 2.1±1.5 | 1.9±1.2 | 0.254 |
| Total cholesterol (mmol/L) | 4.7±1.1 | 5.1±1.1 | 4.6±1.1 | 0.002 |
| Serum sodium (mmol/l) | 139.2±3.1 | 138.7±3.7 | 139.4±2.8 | 0.082 |
| Calcium (mmol/l) | 2.4±0.2 | 2.3±0.2 | 2.4±0.2 | 0.927 |
| Phosphate (mmol/l) | 1.7±0.4 | 1.6±0.5 | 1.7±0.4 | 0.198 |
| hsCRP (mg/L) | 2.9(0.9–8.6) | 4.3(1.4–12.7) | 2.5 (0.8–7.1) | <0.001 |
| RRF (ml/min) | 2.1 (0.0–5.4) | 2.4(0.0–5.2) | 2.0(0.00–5.62) | 0.981 |
| Total Kt/V | 1.9 (1.7–2.1) | 1.8(1.6–2.1) | 1.9 (1.7–2.1) | 0.284 |
| Total Ccr (ml/min/1.73m2/week) | 54.0 (46.2–65.1) | 54.9 (45.9–65.7) | 53.8 (46.2–64.6) | 0.724 |
Abbreviations: CI: cognitive impairment; PD: peritoneal dialysis; DM: diabetes mellitus; hsCRP: high-sensitivity C-reactive protein; RRF: residual renal function; Kt/V, urea clearance per week; Ccr: creatinine clearance per week.