Figure 1.
Synthesis process of the polymer.
Notes: (A) Synthesis process diagram of TC–PECL polymer: i, under the conditions of Sn(Oct)2, methylbenzene, and CH3; ii, under the conditions of 4 M HCl; iii, under the conditions of triphosgene and pyridine; iv, under the conditions of TC and dibutyltin dilaurate. (B) Synthesis process of PECL polymer: under the conditions of Sn(Oct)2 and methylbenzene (i).
Abbreviations: CL, caprolactone; mPEG, methoxy PEG; PCL, poly(ε-caprolactone); PECL, PEG–PCL; PEG, poly(ethylene glycol); TC, tetracycline.