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Overlaid microscopy images of rat osteoblasts subjected to FAM-siRNA transfection in NT-SVTCPM, NT-SVPM, SVTCPM, SVPM, and BK groups at 2, 3, 6, and 12 h after incubation (the siRNAs appear as green signals). 12.6× magnification.
Abbreviations: BK, blank; NT-SVPM, TNTs loaded with SV-loaded PECL micelles; NT-SVTCPM, TNTs loaded with SV-loaded TC-grafted PECL micelles; PCL, poly(ε-caprolactone); PECL, PEG–PCL; PEG, poly(ethylene glycol); SV, simvastatin; TC, tetracycline.
