Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 31;113(46):13069–13074. doi: 10.1073/pnas.1602393113

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. S1. — (A) Forskolin (100 μM) and the water-soluble analog L-858051 (100 μM) stimulate similar cAMP production measured using mCherry-cADDis. (B) Whole-cell mCherry/cADDis ratios are similar in MEFs expressing the mCherry-cADDis sensor or the 5HT6-mCherry-cADDis sensor in nonciliated cells. (C) Three different strategies to target mCherry-cADDis to the cilia, using the 5HT6 receptor, SST3R, or Arl13b. Regardless of the targeting method, ciliary cAMP is similar, indicating that the targeting protein does not affect cAMP levels. Data are presented as mean ± SEM.