Fig. 2.

ATP-evoked Ca²⁺ oscillations: comparison between experiments and simulations. (A) Representative traces recorded from individual nonsensory cells (Left) and corresponding model simulations (Right) for three different [ATP]_es; blue traces are for [Ca²⁺]_c and green for [IP₃]_c. (B) Ca²⁺ dose–response curve for ATP. Each data point represents the average peak [Ca²⁺]_c response of at least 30 nonsensory cells in three different cochlear organotypic cultures; solid line shows model fit to the data.