Fig. S1.

Asymptomatic Tg26 mice exhibit alterations in the BM B-cell compartment. BM cells were collected from age- and sex-matched Tg26 mice and WT control mice and stained for surface markers. The frequency of CD19⁺ among total live cells was similar in the WT and Tg26 mice (Top). Among CD19⁺ cells, IgM⁺IgD⁺ (mature) and CD21⁺ cells were increased in Tg26 mice compared with WT mice. Data are representative of four pairs of mice examined. The increase in CD21⁺CD19⁺ cells in Tg26 BM was significant (P < 0.05, Mann–Whitney U test).