Table S1.

GSEA of hallmark pathways in Tg26 lymphomas

Name	Size*	NES	FDR q
GSEA hallmark pathways: consistency with the most up-regulated genes
E2F	172	3.3005993	0
G2M CHECKPOINT	176	3.2788227	0
MYC TARGETS V1	175	3.0990205	0
MYC TARGETS V2	48	2.3560371	0
DNA REPAIR	134	2.2059152	0
MTORC1 SIGNALING	178	2.1621082	0
MITOTIC SPINDLE	180	2.0368228	0
UNFOLDED PROTEIN RESPONSE	103	1.7171309	0.001916676
SPERMATOGENESIS	123	1.6502607	0.003589697
GSEA Hallmark Pathways: consistency with the most down-regulated genes
ALLOGRAFT REJECTION	172	−2.4777253	0
INFLAMMATORY RESPONSE	184	−2.393372	0
EPITHELIAL MESENCHYMAL TRANSITION	187	−2.326842	0
HALLMARK UV RESPONSE DN	132	−2.2021167	0
APICAL JUNCTION	188	−2.1883261	0
IL6 JAK STAT3 SIGNALING	84	−2.099998	0
IFN GAMMA RESPONSE	172	−2.0646842	1.80 × 10−4
TNFA SIGNALING VIA NFKB	182	−2.054592	1.57 × 10−4
ADIPOGENESIS	183	−1.9837885	3.62 × 10−4
IL2 STAT5 SIGNALING	178	−1.895978	7.39 × 10−4
COMPLEMENT	170	−1.776054	0.001883127
MYOGENESIS	193	−1.7416193	0.002376778
KRAS SIGNALING UP	183	−1.7353489	0.002540431
IFN ALPHA RESPONSE	81	−1.6767852	0.003450024
ANGIOGENESIS	33	−1.6052388	0.007246819
BILE ACID METABOLISM	108	−1.5792547	0.008601794
APICAL SURFACE	42	−1.5046679	0.015674971
HYPOXIA	181	−1.5025636	0.015196791
APOPTOSIS	153	−1.4934539	0.01546518

NES, normalized enrichment score.

^*Number of genes in gene set.