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. 2016 Oct 31;113(46):E7159–E7168. doi: 10.1073/pnas.1605112113

Fig. 3.

Fig. 3.

Distinct roles of the actin and microtubule cytoskeletons in the spatial distribution of the mechanical properties of the cytoplasm. (A) Maps showing the distribution of the shear modulus (G0) in the presence of nocodazole, Taxol, LatA, and CytoD. Data are from n = 44, 56, 24 and 34 beads in cells treated with nocodazole, Taxol, LatA, and CytoD, respectively. (B) Plots of the shear modulus as a function of the distance to the nucleus in control cells (Left) or cells treated with drugs perturbing microtubules (Middle) or actin (Right). (C) Shear modulus gradient obtained by a linear fit of the plots shown in B.