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Ibrutinib is toxic to ABC DLBCL cells. The indicated DLBCL lines were treated with the indicated concentrations of ibrutinib for 6 d and evaluated for viability by trypan blue dye exclusion. The drug was replenished on day 3. Error bars represent mean ± SD of triplicates. The GCB DLBCL cell line OCI-Ly19 served as a negative control cell line.
