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(A) Incubation duration-dependent CLSM images of live HeLa cells when culturing at 37 ℃ with Nile red@mPEG-PCL and Nile red@PPI-PCL micelles. The red channel was excited at 550 nm. (B) Typical time dependence of the emission intensity recorded during the ring-opening reaction of RhB moieties in PM induced by a stopped-flow pH jump from 7.4 to 5.5. (C) Change in the fluorescence emission intensity of PM at 25 ℃ when micellar dispersion pH was cycled between 5.5 and 7.4.
