Table 2.

Regional ALFF differences in patients with RRMS versus HCs

Conditions	Brain regions	R/L	BA	Voxel size	t-score of peak voxel	MNI coordinates (x, y, z)
RRMS > HCs	Fusiform gyrus	R	37	44	4.5473	48, −48, −21
RRMS < HCs	Pons, brainstem	L, R	N/A	43	−4.0505	6, −21, −48
RRMS < HCs	Caudate head	L, R	N/A	206	−4.4563	9, 21, 0
RRMS < HCs	Anterior cingulate gyrus	L, R	24, 32	55	−4.0923	0, 6, 45

Abbreviations: ALFF, amplitude of low-frequency fluctuation; BA, Brodmann area; HCs, healthy controls; L, left; MNI, Montreal Neurological Institute; N/A, not available; R, right; RRMS, relapsing–remitting multiple sclerosis.